Technical Support

Technical Support

FSH Test and Menopause
Coretests, Inc.
The FSH Test manufactured by Core Technology Co., Ltd. is an immunochromatographic one-step assay designed for in vitro qualitative determination of FSH in human urine to evaluate the onset of menopause for women at a concentration of 25mIU/ml or higher.
Follicle Stimulating Hormone is a peptide hormone produced in the pituitary gland of the brain. It is normally present in the blood or urine varying in concentration with the stage of the menstrual cycle. When estrogen levels drop, FSH is released from the pituitary gland either indicating a woman in the mid-menstrual cycle or indicating the onset of perimenopause. During early menopause, changes take place in the balance of hormones that regulate and control menstrual cycles. As a woman grows older and over childbearing age, the ovaries gradually make less of the hormone estrogen, and FSH increases. FSH normally regulates the growth and development of an egg. Once this part of the monthly cycle is complete, FSH production is stopped and it returns to normal. As estrogen production decreases with age, more FSH is made. Over time these hormone changes cause menstrual periods to stop completely and “menopause” occurs.
Health risks that come with menopause usually include osteoporosis, increased blood cholesterol and increased risk of heart disease. The slow change in ovary function can occur between 2 and 10 years before the final period. This early stage before menopause is called Perimenopause. During this stage, the levels of FSH may rise to positive levels and slowly return to normal, causing irregular or missed periods. The testing for FSH should, therefore, be performed twice to help identify the levels of FSH throughout a menstrual cycle.
The FSH Test is a one-step assay for the rapid qualitative determination of FSH in the urine. The immunological specificity of the test kit virtually eliminates cross-reactivity and interference with structurally related glycoprotein hormones such as hLH, hCG and hTSH.